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Liquid-liquid Extraction System Based on Non-ionic Surfactant-salt-H2O and Mechanism of Drug Extraction
Abstract: Extraction behavior of chlorpromazine hydrochloride (CPZ) and procaine hydro-
chloride (PCN) in the system described in the title was studied. Research shows that the
extraction efficiency of CPZ can amount to 96% by twice extraction, while that of PCN is 77%.
This system produces the distribution coefficients (KD) of 12.3 and 2.6 respectively for CPZ and
PCN. Extraction mechanism is deduced according to ultraviolet and molecular fluorescence
spectra variation of the drugs in the system studied.
Keywords: Non-ionic surfactant-salt-H2O extraction system, polyethylene glycol-1000, chlor-
promazine hydrochloride, procaine hydrochloride, mechanism of extraction.无忧论文 【http://www.uklunwen.com】 |
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